9 Types of Medications That May Cause Insomnia
Having trouble falling asleep, staying asleep, or waking up earlier than expected? Your medication may be contributing to your sleep problems. Some prescription and over-the-counter medications can increase alertness, cause restlessness, or trigger side effects that interfere with a good night’s sleep.
Medications That Can Interfere With Sleep
- Cold and allergy medications
Decongestants containing pseudoephedrine or phenylephrine may cause increased alertness, jitteriness, or difficulty sleeping. - Blood pressure medications
Some beta blockers and ACE inhibitors may contribute to sleep issues, including insomnia, vivid dreams, coughing, or leg discomfort. - Pain relievers
NSAIDs may cause stomach irritation that disrupts sleep, while some headache medications containing caffeine may make it harder to fall asleep. - Antidepressants
Certain SSRIs and bupropion may increase alertness or interfere with the ability to fall asleep. - Smoking-cessation products
Nicotine patches, gum, lozenges, and some prescription treatments may affect sleep patterns or cause nighttime restlessness. - Corticosteroids
Medications like prednisone may have a stimulating effect, especially when taken later in the day. - Asthma and COPD medications
Some inhalers and respiratory treatments may cause side effects such as nervousness, a faster heartbeat, or trouble sleeping. - Stimulant medications
ADHD and narcolepsy medications may affect sleep, especially when taken too late in the day or at higher doses. - Dopamine agonists
Certain medications used for Parkinson’s disease or restless legs syndrome may contribute to insomnia or disrupted sleep.
What Can You Do?
Never stop taking or change your medication without first speaking with your healthcare provider. They can help determine whether changing the timing, adjusting the dosage, or switching medications may improve your sleep quality.
For certain medications, taking them earlier in the day may help minimize sleep-related side effects.
Reviewing your medications with a healthcare provider can be an important first step toward achieving better sleep.